CHAOSTOCOSMOS

Thursday, 7 April 2016

Microstructural Havoc: The Immune System, Fatigue and the Brain - An ME/CFS and FM Scenario

The authors believe these changes reflect changes in, get this, lactate – which we’re seeing more of in both ME/CFS and FM – and pH in this region of the brain. Increased lactate or lactic acid levels appear to be present in the brains, muscles and possibly guts of fibromaylgia and ME/CFS patients. Increased lactate levels also predicted which GWS patients were able or unable to exercise. Increased brain lactate levels also appears to be triggering migraines when low oxygen conditions are present. High lactate levels, then, are showing up in several related disorders. That’s good news for those looking for a common thread in these disorders. It turns out that the basal ganglia are “exquisitely vulnerable” to several factors that could be occurring in ME/CFS/FM – hypoxic (low oxygen level induced injuries), viral invasion and neurodegenerative processes. Given what we know low oxygen conditions could fit very well with what is happening in ME/CFS.

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Microstructural Havoc: The Immune System, Fatigue and the Brain - An ME/CFS and FM Scenario

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