"The differing effects of the gut flora on symptoms in men and women was intriguing given studies showing very high rates of gynecological disorders in women with ME/CFS. Those studies and others suggest that estrogen, an immune regulator among other things, could play a role in producing ME/CFS. Broderick’s immune studies suggest that testosterone, on the other hand, may play a protective role for me. The authors noted that the gut flora can effect estrogen production."
Gender Gut Wars: Australian ME/CFS Study Suggests Different Gut Treatment Protocols Needed For Men and Women