|Typical food triggers immune tolerance in the small intestine. Credit: IBS|
Researchers document how normal diet establishes immune tolerance conditions in the small intestineOur immune system evolved to attack foreign materials entering our body. Food is technically foreign, but it is somehow tolerated by the immune system so that our body can absorb the nutrients. The immune system has built-in tolerance mechanisms that harness itself from responding to benign foreign antigens beneficial to our system, like food. When such tolerance fails, we suffer from an overt immune reaction, such as food allergies, which can be severe enough to be fatal. Despite the increasing incidence and severity of food allergies, the details on how immune tolerance to dietary antigens is normally established remain largely unknown. Scientists from the Academy of Immunology and Microbiology (AIM) within IBS in South Korea have recently uncovered one of the key mechanisms in the small intestine that triggers this process.
Typical food triggers creation of regulatory T cells