AHRG’s researchers have begun to converge on a promising theory about what really causes hangovers: namely, that they’re an inflammatory response, like what happens when we get an infection. A team in Korea noticed that hangovers are accompanied by elevated levels of molecules called cytokines, which are used as communication signals by the immune system. If you inject those into a healthy subject, that person will start to have all kinds of familiar-sounding symptoms, including nausea, gastrointestinal distress, headache, chills, and fatigue. Potentially even more interesting, higher-than-normal cytokine levels also interfere with memory formation—which might account for ethanol-related lapses in recall as well.Hangovers aren't caused by dehydration, low blood sugar, or acetaldehyde
Saturday, 2 January 2016
Hangovers aren't caused by dehydration, low blood sugar, or acetaldehyde
If you're familiar with ME/CFS and fibro, then inflammatory response, cytokines, the immune system and gamma aminobutyric acid (GABA) are certainly not new terms to you. Might this also explain why we often feel like we have a hangover, even when we haven't had a drink and, why we often have varying and variable levels of intolerance to alcohol? It's going to take a heck of a lot more than a bit of Ibuprofen to sort us out, but maybe something in this research will lead to something that might also give us some symptomatic relief.