Tuesday, 22 December 2015

Gammaherpesvirus Infection of Human Neuronal Cells

Gammaherpesviruses human herpesvirus 4 (HHV4) and HHV8 are two prominent
members of the herpesvirus family associated with
a number of human cancers. HHV4, also known as
Epstein-Barr virus (EBV), a ubiquitous gammaherpesvirus prevalent in 90
95% of the human population, is clinically
associated with various neurological diseases such as primary central
nervous system
lymphoma, multiple sclerosis, Alzheimer’s
disease, cerebellar ataxia, and encephalitis. However, the possibility
that EBV
and Kaposi’s sarcoma-associated herpesvirus
(KSHV) can directly infect neurons has been largely overlooked.

Gammaherpesvirus Infection of Human Neuronal Cells

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