CHAOSTOCOSMOS

Wednesday, 27 May 2015

Mitochondrial Depletion Could Underlie the Energy Problems in Chronic Fatigue Syndrome

Very, very few chronic fatigue syndrome studies have emerged from Germany, but the last two have been good ones. The one before this was the first to find evidence of EBV activation in ME/CFS, in years. This one – a model exploring mitochondrial dynamics – may help explain what’s causing the post-exertional problems, published in the Biophysical Chemistry journal, this study extended a well-known metabolic model explaining what happens to the mitochondria in the skeletal muscles during exercise. The authors enhanced it by adding some processes to it (lactate accumulations / purine degradation) known to occur in the mitochondria. In silico analysis of exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome. Nicor Lengert, Barbara Drossel Institute for Condensed Matter Physics, Technische Universitat. Biophysical Chemistry 202 (2015) 21–31



Mitochondrial Depletion Could Underlie the Energy Problems in Chronic Fatigue Syndrome

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