CHAOSTOCOSMOS

Monday, 6 October 2014

The CFS/ME Brain Is Inflamed

For most people with Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (CFS/ME) central nervous system function is abnormal. However, we don’t understand the mechanisms involved. Many experts suspect an inflammatory component, but the results from cytokine studies of cerebrospinal fluid have been uncertain.

Now, researchers at the RIKEN Center for Life Science Technologies in Hyogo, Japan, have directly measured neural inflammation using a combination of PET scan and MRI imaging. (1)

Their key findings: Compared to healthy controls, nine patients with CFS/ME showed evidence of abnormal activation of microglia and/or astrocyte immune cells within the brain. In specific brain areas the degree of immune activation correlated closely with the severity of the patients’ symptoms.

The CFS/ME Brain Is Inflamed

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