CHAOSTOCOSMOS

Wednesday, 5 March 2014

Mitochondrial dysfunctions in Myalgic Encephalomyelitis / chronic fatigue syndrome explained

Mitochondrial dysfunctions have been found in ME/cfs, e.g. lowered ATP production, impaired oxidative phosphorylation and mitochondrial damage. This paper reviews the pathways that may explain mitochondrial dysfunctions in ME/cfs.

It is argued that mitochondrial dysfunctions, e.g. lowered ATP production, may play a role in the onset of ME/cfs symptoms, e.g. fatigue and post exertional malaise, and may explain in part the central metabolic abnormalities observed in ME/cfs, e.g. glucose hypometabolism and cerebral hypoperfusion.

Mitochondrial dysfunctions in Myalgic Encephalomyelitis / chronic fatigue syndrome explained

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