CHAOSTOCOSMOS

Wednesday, 22 January 2014

Deficient EBV-Specific B- and T-Cell Response in Patients with Chronic Fatigue Syndrome

When comparing EBV load in blood immune cells, we found more frequently EBER-DNA but not BZLF-1 RNA in CFS patients compared to healthy controls suggesting more frequent latent replication. Taken together, our findings give evidence for a deficient EBV-specific B- and T-cell memory response in CFS patients and suggest an impaired ability to control early steps of EBV reactivation. In addition the diminished EBV response might be suitable to develop diagnostic marker in CFS.

Deficient EBV-Specific B- and T-Cell Response in Patients with Chronic Fatigue Syndrome

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