Wednesday, 23 January 2013

The muscle in ME: It isn't ALL deconditioning!

Should ME patients exercise? Much of the current thinking about CFS and ME is driven by models of deconditioning and the notion that a little regular exercise will be beneficial. That is true; some exercise is good for us all. But what if exercise results in a huge delivery of free radicals, not because of disuse of muscle and deconditioning, but because there is something organically wrong with muscle metabolism? What value exercise in these circumstances?

These are crucial questions, and it is important to remember that the current evidence for deconditioning is not based on scientific investigations of muscle, but on suppositions about patients with "fatigue".

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