Tuesday, 23 August 2016

Lipkin’s Monster ME/CFS Study: Microbes, Immunity & Big Data

Columbia University’s Center for Infection and Immunity(CII) has seriously upped the ante on the initial microbe discovery project in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Their impressive, rigorous new study could point the way to diagnostic tests, and even treatments – but first they need the funds to complete the work.

Lipkin’s Monster ME/CFS Study: Microbes, Immunity & Big Data

Saturday, 20 August 2016

Chronic Fatigue Syndrome: tribunal orders data from controversial trial to be released

A tribunal has ruled that data from a controversial £5m treatment trial into Chronic Fatigue Syndrome (CFS) must be released, rejecting an appeal from the university that had carried out the study.

Chronic Fatigue Syndrome: tribunal orders data from controversial trial to be released

Friday, 19 August 2016

Federal Report Says There's (Almost) No Evidence CBT/GET Work in Chronic Fatigue Syndrome (ME/CFS)

Hopefully the AHRQ’s reanalysis will help the blunt the emphasis given to CBT/GET in this field. What this field really, really, really needs,though, is to end the dominance of European government funded behavior based trials. No two entities should be able, simply by pouring money into a field, to dictate its treatment options, but that’s essentially what’s happened in ME/CFS.

Federal Report Says There's (Almost) No Evidence CBT/GET Work in Chronic Fatigue Syndrome (ME/CFS)

Monday, 8 August 2016

August 8th, 2016: Understanding and Remembrance Day for Severe Myalgic Encephalomyelitis

August 8th, 2016 is Understanding and Remembrance Day for Severe Myalgic Encephalomyelitis, an important day in the ME community. It’s a day that is intended to bring attention to those whose voices are the most quiet, whose presence is so easily overlooked.

August 8th, 2016: Understanding and Remembrance Day for Severe Myalgic Encephalomyelitis

Sunday, 31 July 2016

Spinal fluid abnormalities in patients with ME/CFS

Our outcome measures were white blood cell count, protein concentration in spinal fluid, and cytokines detectable in spinal fluid. We found that significantly more CFS patients had elevations in either protein levels or number of cells than healthy controls (30 versus 0%), and 13 CFS patients had protein levels and cell numbers that were higher than laboratory norms; patients with abnormal fluid had a lower rate of having comorbid depression than those with normal fluid.

Spinal fluid abnormalities in patients with ME/CFS

The Blood Volume Paradox in ME/CFS and POTS

Kunisha Miwa has published no less than five studies on the small heart findings in ME/CFS. Now he moves onto a related puzzle – why the blood volume in ME/CFS is low? Health Rising takes a look at his present study, combines his findings with some others, and comes up with a possibility.

The Blood Volume Paradox in ME/CFS and POTS

Monday, 25 July 2016

The Zinn's Find an Under-Active Brain in Chronic Fatigue Syndrome (ME/CFS)

If your attention span has become shorter, if you can’t remember things, if you often lose your train of thought, if you make silly mistakes, even if you’re anxious a lot or can’t move well – the good news from this study is that that’s not you – it’s probably your brain.

The Zinn's Find an Under-Active Brain in Chronic Fatigue Syndrome (ME/CFS)

Saturday, 23 July 2016

The Fatigue and Pain Hormone? Leptin Shows Up Again - in Fibromyalgia

Nobody in the chronic fatigue syndrome (ME/CFS) community had taken leptin – a hormone produced by fat cells – seriously until Jarred Younger’s Stanford Good Day Bad Day study suggested that it might be the factor driving fatigue n ME/CFS. Younger wasn’t aiming at leptin; it was just one of many immune factors he analyzed in his unusual (and intense) study examining the blood of ME/CFS patients over 25 days. Now leptin is popping out again – this time in women with body-wide pain and fibromyalgia.

The Fatigue and Pain Hormone? Leptin Shows Up Again - in Fibromyalgia

Tuesday, 19 July 2016

Fibromyalgia Study Points to Inflammation, Damage and Low Energy Production in Muscles

The encouraging thing about this study was not that it found some proteins but that the proteins in the muscles of FM patients found fit so well with what we suspect about it. In my experience “omics” (proteomics, genomics) studies often come with an array of factors, many of which just don’t seem to fit but most of the proteins that showed up in this study fit FM really well; i.e. they were associated with cellular stress, inflammation, muscle damage and problems with energy production.

Fibromyalgia Study Points to Inflammation, Damage and Low Energy Production in Muscles

Monday, 18 July 2016

Fresh evidence points to a cause and possible treatments for chronic fatigue syndrome

Chronic fatigue syndrome, or myalgic encephalitis, has been largely dismissed as psychological. But recent trials of antiviral and immunosuppressant drugs have yielded encouraging results, suggesting a complex disease mechanism at play that researchers are hopeful they might be able to treat.

Fresh evidence points to a cause and possible treatments for chronic fatigue syndrome
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